Introduction
With bonnet, and Maastricht University tie |
With bonnet, and Maastricht University tie |
Katalin Karikó is a Hungarian-born biochemist who is widely recognized as one of the pioneers of messenger RNA (mRNA) technology, which has revolutionized the field of vaccine development and led to the creation of the highly effective COVID-19 vaccines by BioNTech/Pfizer and Moderna. ¹²³ This year she received the Nobel Prize for medical physiology for her work.
However, before she achieved this remarkable feat, she faced decades of rejection, frustration, and demotion at the University of Pennsylvania, where she worked as a researcher from 1989 to 2013. ⁴⁵
In this blog post, I will explore how the university culture at Penn failed to appreciate and nurture Karikó's talent and vision, and how this reflects on the challenges and limitations of academic research in general.
One distinguishing feature of my career, it that I have lived and worked in many different countries, something I always chose to do out of my own initiative. In fact, two thirds of my working life I spent in the Global South. I lived in some of the poorest countries in the world, some ravaged by civil strife, where child mortality is high and life expectancy short. In some of these countries, polio, cholera and leprosy are still common. Sadly, in Papua New Guinea for example, even tribal warfare and witch burning are still regular occurrences and widely reported in the newspapers. In a few weeks, I will be starting a new professional challenge in a neighboring European country, a few hours' drive away. For me a minor transition.
Lecturing about research support at universities in 2010 in Turkey |
Friends and family often ask me why I am moving again. The short answer is that I always seek decent, meaningful work and respectful employers so that I can contribute to my community and society at large. However, the longer answer is more complex. Looking back, the main reasons for moving about can be partly attributed to "Fortuna" or fate, partly my decisions to leave when prospects seemed dim, and partly due to my value-based choice for meaningful work and making a difference in the world.
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During the past two centuries, most countries have successfully established primary and secondary school systems and made education compulsory for a number of years. However, the emphasis has primarily been on access and enrollment, and many children who attend school are not actually learning. Shockingly, over 600 million children and adolescents worldwide are unable to reach the minimum proficiency levels in reading and mathematics, despite two-thirds of them attending school according to UNICEF.